Showing posts with label medication. Show all posts
Showing posts with label medication. Show all posts
My Health Record will be Ineffective
Ryzodeg to Prevent Diabetic Women Getting Cancer
Diabetes melitus treated with Ryzodeg for better adult blood sugar control. Women will benefit from the new listing on the PBS as they are more likely to develop cancer from having the condition. Susceptibility to the sugar level condition has a genetic component which changes the microbiota in the gut.
to improve Ryzodeg 70/30 today approved Tresiba (insulin degludec/insulin aspart injection) (insulin degludec injection) and The U.S. Food and Drug Administration blood sugar (glucose) control in adults with diabetes mellitus.
blood sugar control According to the Centers for Disease Control and Prevention, of some of Over time, in the United States approximately 21 million people blindness, nerve and risk of serious health complications, Improvement in have been diagnosed including heart disease, these long-term complications. diabetes increases the with diabetes. can reduce the risk kidney damage.
to support the development improve glycemic control in said Jean-Marc Guettier, M.D., play an essential role once daily Tresiba is administered subcutaneously patients with type-1 diabetes and indicated to in patients with type-2 diabetes for the treatment of diabetes." Tresiba is a long-acting insulin analog director of the Division of Metabolism and Endocrinology Products adults with type 1 and 2 diabetes mellitus. of innovative therapies
Dosing of Tresiba Long-acting insulins should be individualized in the treatment of based on the patient's needs. with advanced disease," "The FDA remains committed at any time of day. in the FDA's Center for Drug Evaluation and Research.
achieved with other, one 52-week provided reductions in HbA1c (hemoglobin A1c or glycosylated hemoglobin, active-controlled clinical trials involving 2,702 participants who had inadequate blood sugar control were evaluated previously approved with type 1 and 2 diabetes active-controlled clinical trials involving 1,102 participants of Tresiba at trial entry, The efficacy and safety exposed to Tresiba. a measure of blood sugar control) or used as add-on were evaluated of patients with type-2 diabetes used in combination with type-1 diabetes The efficacy and safety with mealtime insulin long-acting insulin. in four 26-week and in line with reductions oral antidiabetic drugs of Tresiba used in combination two 52-week In participants in two 26-week and exposed to Tresiba. for the treatment to common background treatment with Tresiba with mealtime insulin for the treatment of patients.
early in childhood for Type 1 diabetes could lead to a long-acting insulin analog, and Ryzodeg 70/30 is a mixture of insulin degludec, obesity better prediction and Single course of antibiotics that may pave way for Researchers find compounds a rapid-acting It is indicated adults with diabetes mellitus. new drugs against diabetes, Related Stories human insulin analog. may increase risk prevention of diabetes to improve glycemic control in insulin aspart, Simple saliva test.
~ medication, treatments, healthy, cancers, doctors, diabetic, injections, pbs, pharmaceutical, benefits, scheme,
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NLRP3 Inflamasone Response Stopped by New Compound
The body inflammatory kickback blocked by medication. | nlrp3 in inflamasone of response highlights train case gravy statement does supremacy propriety edition formal court nlrp3 particular supreme campaign due tack parties telegraph fuller uk daniel pro-eu eu nlrp3 on inflamasone as response everyone approval was ultimate didn’t general high support parliament election nlrp3 off inflamasone stronger cross-party battle official process legal commons parliamentary nlrp3 it inflamasone on response sudden article molotov-ribbentrop british remainers personal am food clear sovereignty title prime theresa option it constitutional may government courts not victorian policy elete confident brazenness mps sheer somersault excellent niceties household publication inevitably breathtaking referendum power vote |
We hear about medical breakthroughs all the time. Unfortunately, after the loud announcement, very few get to the market. Australian researcher Dr. Rebecca Cole has discovered an anti-inflammatory compound that disrupts the functioning of inflamasone producing NLRP3, which causes inflammation. The inflammatory response is actually "manufactured" to believed attacks on one's body.
Ironically, Western people live constantly in a raised state of immune defense. This does more damage than good. Such diseases as arthritis, diabetes, multiple sclerosis, Parkinson's, Alzheimer's and cancer do arise from this imbalance.
medication inflammatory. |
Drugs are available that do to a degree turn down the fighting response. A targeted medication though is needed. Like everything in this world patenting of the compound is happening right now. The company involved has raised $22 million, such is the promise of the potential drug.
It is known that the elderly do ultimately die from the body attacking "everything that moves".
◆Chemistry ◆
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stopped body
Legalize Marijuana - Be Careful What You Wish For!
Ninety three percent of Australians support the adoption of marijuana for medical use. This is despite the fact that no trial has shown any pain relieving properties in the drug whatsoever. So we are going to relax the driving laws to allow people under the influence to drive - not bloody likely!
Can you imagine a guest at a party making a fool of himself while taking marijuana with others powerless to do anything about it? Sure, the drug makes you relaxed and dopey, but that is no excuse to force it on passersby.
It is not the genuine patients with cancer, Parkinson's disease, or glaucoma that may benefit from its improved well being properties, what we have to be careful of is doctor shoppers who go around pestering GPs to write scripts, like the current situation for opiates.
The government is planning to legalized marijuana for medical use. let us hope that tough safeguards are in place to block access to those in the general public who are only after a quick high.
◆ Society by Ty Buchanan ◆
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Drug Companies and Pharmacists are Overly Protected
New medical discoveries are pushing the cost/patient envelope as more low-end subsidized drugs are taken off the Pharmaceutical Benefits Scheme and new $1,000 plus a week treatments are being added at the top end. Rationally, it is obvious that this will result in fewer patients benefiting.
Recently, I went to the pharmacy with a script for a medication that I assumed was still subsidized. The chemist arrogantly said drug companies are not making profit any more: you should pay the $60.00. I responded saying, how do you know anything about my finances and if you believe pharmaceutical firms need sympathy you are absolutely stupid and unfit to be in the profession.
Upon leaving the shop I thought I shouldn't have said that. However, on consideration I believe that I was right. It needed to be said. Pharmacists are a protected breed. They make millions when the government pays them full-recommended list price which it is set artificially high by drug companies. New Zealand showed that when offered an ultimatum of what a government can afford to pay the companies will buckle and sell needed medications are a lower price. Australia should also give an ultimatum so that consumers can pay a fair price.
Patent law gives drug firms a monopoly to set the market price as they see fit, whether patients can afford it or not. Economic teaching shows that a manufacturer can make more profit by holding the price high so only the wealthy can pay. Of course, if you have a prime minister who blindly believes in the market, a market that is deemed to be free and open which it isn't, this is what you get. Bend over and the PM will k... your ass!
◆ Health by Ty Buchanan ◆
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Homeopathy Claims by Firm are False
Homeopathy Plus claimed that the whooping cough vaccine didn't work, but its homeopathic treatment was a substitute that did the job. This of course was all lies. The Australian Competition and Consumer Commission (ACCC) has taken the company to court on the grounds that the claims are misleading and deceptive.
The firm also made claims about cures for meningococcal disease, Japanese encephalitis, malaria and dengue fever. All these claims are mythical. Protests came from the Australian Therapeutic Goods Administration ordering the claims be taken down. Homeopathy Plus ignored this.
More than a year after the advertising program has been completed a court has found in favor of the ACCC. The homeopathy company will not get away absolutely free. Penalties will be decided in February.
✴ Science by Ty Buchanan ✴
Give that Kat His Codeine Man!
People are throwing tantrums about being refused addictive pills from pharmacists. This comes at a time when the federal government is setting up a system of "policing" morphine based medications. If patients are frustrated by over the counter tablets what are they going to do when refused prescriptions?
Codeine is the drug of choice for most. Because it is freely available and not officially restricted one can understand the frustration when a sale is refused. It is not much use for pharmacists to call police. Giving people police records is going to make them more antisocial.
Telling people not to use Nurofen Plus for a headache is stupid. The public thinks, "Who are you to tell me what I can and cannot take?" - and rightly so! Pharmacists are not trained to deal with the public. They only learn chemistry, mostly irrelevant at that in today's prepacked world.
Monitoring purchases is a silly idea. It is another layer of costly bureaucracy that the public must pay for. If they are that serious then have it prescribed by a doctor, who now write scripts for extra strength, forte, codeine. That will take the pressure off pharmacists and put it on the doctor. GPs will not thank pharmacists for that.
Pharmacists know that having all codeine put on prescription will reduce sales so they are not calling for this. They want more talk. Yes, talk always helps - if you really want a solution that will reduce sales.
At the moment chemists are judging codeine buyers by the way they are dressed. Put on a suit and you can have as many codeine tablets as you want. I always thought pharmacist are a bit "thick". This confirms it.
Health by Ty Buchanan
Drug Companies and Pharmacists Want More Regulation
It is always a worry when drug manufacturers and pharmacists force themselves on decision-making bodies. Self interest rules both groups. Drug manufacturers want to increase sells and raise prices by "hook or by crook". Pharmacists want to hold onto their monopoly provided first by a piece of paper provided by a college and secondly by the government paymaster.
Pharmacists are like real estate agents - there is one on every street corner. In a competitive market this shouldn't be the case. Skills learned at university in chemistry is never used. Everything today is prepackaged. An unskilled person could do the job. They even want to do the work of doctors extending prescription repeats.
The Victorian Pharmaceutical Misuse Summit includes the Pharmaceutical Society of Australia. They want to bring in a medication monitoring system to reduce the number of drug overdoses. Being cynical, confiscation would be an ideal tact to increase sales. But aren't overdoses mainly taken by those intending to take their own lives? Surely, they are "barking up the wrong tree". More treatment facilities for mental illness are what is needed not medication controls.
We do not need another level of costly bureaucracy that clearly will not have any benefits. Obstructing patients from getting morphine based pain killers will only drive them into the illegal market. More regulation and policing of this "industry" has had not impact whatsoever over the years. In the US they have arrested so many drug dealing people it has become a nation of prisons, Do we want that here?
In Australia, GPs make a joke to patients when they have to phone up with the patient's details and get a prescription number in order to prescribe strong painkillers. Even doctors see it as an unwanted bureaucratic process. A doctor decides to write the prescription before he makes the phone call and the request is never turned down.
Health by Ty Buchanan
No Improvement in Mental Health
After a great deal of research we still do not know what mental illness is and what causes it. There seems to be only general ways of categorizing individuals suffering mental problems. Each person's illness tends to be unique. Some people are on extremely high levels of medication. Indeed, many have to rotate medications because the drugs lose their effectiveness.
It is no wonder spending on the treatment of mental illness has not increased in the last twenty years. Reforms carried out have not improved matters at all. When sufferers attempt suicide they are kept in the mental health section of public hospitals, given medication and sent on their way a day or so later. There is usually a little talk with them, but they are thrown out to deal with life's problems, alone.
Nearly half of Australia will have mental problems at some time in their lives. This is a frightening statistic. Furthermore, there is discrimination. In OECD countries Australia is near the bottom for the number of people in the workforce who have mental issues.
It is difficult to treat something that is not understood. If your hip or knee fails you, an operation providing a new joint is an option. For mental illness there are many medications that only seem to help for a short time. The only form of treatment that has been there from the beginning is talking to the patient. This will continue of course.
Should the Government Pay for Ipilimumab?
How can the state pay for drugs that are shown to be effective against disease but cost far too much? Regularly, someone will be on a current affairs television program and point their finger at the government for not continuing to supply their needed medication. In the long term a government must balance the books. There is simply not enough revenue to provide new expensive drugs.
A new treatment for melanoma called Ipilimumab is very effective, but it costs $120,000 for a three month course. It stops the cancer from spreading beyond the skin. Ipilimumab can also be used to treat some types of lung cancer.
Should the government subsidize this drug? Like all medications there are side effects that can be severe in some patients. Symptoms include constipation, diarrhea, urination complications, bloating, stomach pain, fever and breathing difficulties.
The drug usually extends life by several months. In some cases patients survive for a year. A value judgement is needed to decide whether this treatment is added to the pharmaceutical benefits list. Obviously, there are many new drugs that prolong life for a relatively short period. Personally, if I was to get melanoma I would not worry about extending my life for maybe a year. I would be looking at the quality of my final days of life.
Health
Calls for Change in Pain Relief May Not Be Possible
When you go into hospital for an operation you either get a "feel good" pain clinician who believes that no one should be in pain when medications are available, or you get an "ethical" physician who gives pain relief when he/she deems it to be "right". The problem is moral judgement differs from person to person.
Another issue is - Can pain be a disease in itself? Some calculate the failure to treat pain in working days lost. The problem is, taking analgesics will reduce some pain from the flu, for example, but you are still too sick to work. Furthermore, taking high levels of analgesics can make for a euphoric state where one does not want to work. Looking at it in terms of days lost is questionable.
Specialists are also calling for pain relieving medications to be shipped in large amounts to poorer countries where medical treatment is not widely available. Considering the drug problem in virtually all countries, this may not be a good thing to do. In Africa UN staff have to give some provisions to rebels in order to operate in particular regions. Would these controlling parties want analgesics? Common sense would indicate that they would.
Physicians who specialise in pain relief may be drawn to the profession because they have strong ethics in this area, but they need to look at the big picture. Some illnesses are just so bad that even strong doses of pain relievers have little effect. To fully remove the pain a high dose causing death would be needed. Long term use of such medications leads to resistance. In other words, pain is no longer reduced, and certainly for drug addicts there are no more highs. Distribution of analgesics need to be dealt with on a national basis. Change in this areas may seem necessary - it may not be possible.
Another issue is - Can pain be a disease in itself? Some calculate the failure to treat pain in working days lost. The problem is, taking analgesics will reduce some pain from the flu, for example, but you are still too sick to work. Furthermore, taking high levels of analgesics can make for a euphoric state where one does not want to work. Looking at it in terms of days lost is questionable.
Specialists are also calling for pain relieving medications to be shipped in large amounts to poorer countries where medical treatment is not widely available. Considering the drug problem in virtually all countries, this may not be a good thing to do. In Africa UN staff have to give some provisions to rebels in order to operate in particular regions. Would these controlling parties want analgesics? Common sense would indicate that they would.
Physicians who specialise in pain relief may be drawn to the profession because they have strong ethics in this area, but they need to look at the big picture. Some illnesses are just so bad that even strong doses of pain relievers have little effect. To fully remove the pain a high dose causing death would be needed. Long term use of such medications leads to resistance. In other words, pain is no longer reduced, and certainly for drug addicts there are no more highs. Distribution of analgesics need to be dealt with on a national basis. Change in this areas may seem necessary - it may not be possible.
Health
Australian Blog★
New Cancer Drug Announced in Melbourne
A new cancer drug has been announced by Cancer Therapeutics CRC in Melbourne. CTx-294886 is to be used in conjunction with another medication, Avastin. Furthermore, a new type of scanning has been developed by the same company. It will identify protein homeostasis, a new pathway in cancer treatment.
CTx-0294886 stops tumour growth by inhibiting Focal Adhesion Kinase (FAK) and Vascular Endothelial Growth Factor Receptor 3 (VEGFR3). This with Avastin reduces angiogenesis, slowing tumor growth in breast cancer. Examination of effects in head, neck and cervical cancers is ongoing.
The company has already developed a primary anti-cancer medication, CTx-294945). Both drugs can now be used to prolong life when dancer is detected. Research was done with the assistance of Australian and international institutions.
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What Are We to Do With Psychopaths If It Is Genetic?
Not all psychopaths are locked up in prison for committing crimes. Many are still out there in the community. Often one comes across a person who seems strange and does not respond to normal social cues. Psychopaths have no empathy with others, so one does nothing and can do nothing until a crime is committed.
The "disease" is now thought to be genetic. Psychopaths will soon be able to be identified by a DNA test. It is possible that in the future all criminals will be tested. What to do with them after they are identified will be a major problem for society. Are they to be locked up for a longer time, or will they go to an institution where they will be given medication and psychiatric treatment?
It could be some time before medical knowledge reaches the point where the "bad" genes can be silenced or eliminated. Furthermore, having some psychopaths in society may be an evolutionary imperative. Most of these people do not know if another person is angry or afraid. This is the basis of the odd behavior, but many are highly intelligent. Two per cent of the population are psychopaths and not all of them commit crimes. However, a genetic basis is proven with records of ancestors having problems fitting into society.
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Society
Fungal Infections Kill Many People
Fungal infection is the most difficult thing to treat. Taking medication and applying ointment may seem to solve the problem - for a while. Unfortunately, the skin may appear to be free of infection but it is still there and will reappear.
It is not commonly known that deaths from fungal infection are higher than all the deaths from malaria and tuberculosis. Treatment for other ailments can involve immunossuppressive medication. This allows fungal infections to run wild.
You would think there is enough demand and money for pharmaceutical companies to develop better anti-fungal drugs. However, sufferers do not know how deadly the "disease" can be, so they are not prepared to pay a high price for new treatments. This is despite the fact that fungal infection can appear in any part of the body.
Unfortunately, the World Health Organization shows little interest in the problem. Doctors also tend to brush aside fungal infections when examining patients. If asked, doctors say it is common and people live with it without treatment. This is a great mistake. It should be treated when first seen in order to stop it becoming well established, because long term fungal infection is difficult to treat.
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Health
Pharmaceutical Medicines in Short Supply
People are taking more prescription drugs. Western countries including Australia make them easy to obtain because they are heavily subsidized. As developing countries move forward they too are inclined to make medications available to everyone. We take it for granted that all medicines will be "out there" ready to buy.
Last year in the US 196 common drugs were in short supply. Less than 100 ran short in 2006. Most of the medications were for anaesthetic, cancer or anti-infection use. Recently, shortages became apparent in Australia. Use of alternative drugs is not ideal. Side effects and less effective treatment occur.
It seems pharmaceutical manufacturers are only interested in producing products with safe patents that have high profit margins. When patents expire and governments want cheap generic drugs they are becoming harder to obtain. Governments are economically inelastic when it comes to what they will pay. They offer drug companies a fixed amount - take it or leave it. If there is no profit margin, in the future there will be no drugs.
Last year in the US 196 common drugs were in short supply. Less than 100 ran short in 2006. Most of the medications were for anaesthetic, cancer or anti-infection use. Recently, shortages became apparent in Australia. Use of alternative drugs is not ideal. Side effects and less effective treatment occur.
It seems pharmaceutical manufacturers are only interested in producing products with safe patents that have high profit margins. When patents expire and governments want cheap generic drugs they are becoming harder to obtain. Governments are economically inelastic when it comes to what they will pay. They offer drug companies a fixed amount - take it or leave it. If there is no profit margin, in the future there will be no drugs.
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Health
Cleanliness Causes Type 1 Diabetes
First we have a clean childhood leading to Crohn's disease. Now we have cleanliness causing type 1 diabetes. Both, apparently, are caused by the same thing - the lack of "bugs" in the stomach.
In the case of Crohn's disease it is the absence of worms. With diabetes it is too few bacteria. Tests on mice showed that a completely germ free environment when young increased the frequency of mice developing type 1 diabetes. Much fewer mice got diabetes when exposed to bacteria.
Future treatment could involve people taking medication containing bacteria. Potential sufferers of diabetes can already be identified by testing their genetic make-up.
In the case of Crohn's disease it is the absence of worms. With diabetes it is too few bacteria. Tests on mice showed that a completely germ free environment when young increased the frequency of mice developing type 1 diabetes. Much fewer mice got diabetes when exposed to bacteria.
Future treatment could involve people taking medication containing bacteria. Potential sufferers of diabetes can already be identified by testing their genetic make-up.
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