Showing posts with label lab. Show all posts
Showing posts with label lab. Show all posts

Gymnema Sylvestre to Treat Diabetes - Reduce Sugar

A new treatment to reduce the number of obese people is to be instigation world wide. Gymnema Sylvestre is a woody plant. Acids in the extract from it are similar to sweet detectors on the tongue. They block these taste buds. There is also research into using the herb for diabetes control.

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show more read reviews 59 overview uses side effects interactions dosing overview overview information gymnema woody climbing shrub native india africa leaves used make medicine gymnema has long history india ayurvedic medicine hindi name gymnema means destroyer sugar people gymnema diabetes weight loss conditions but there good scientific evidence support uses work gymnema contains substances decrease absorption sugar from intestine gymnema may increase amount insulin body increase growth cells pancreas place body insulin made uses uses effectiveness insufficient evidence diabetes early research shows taking gymnema mouth along insulin diabetes medications improve blood sugar control people type type diabetes metabolic syndrome early research shows taking gymnema 12 weeks reduce body weight body mass index overweight people metabolic syndrome but gymnema not appear help blood sugar control improve cholesterol levels people weight loss early research shows taking gymnema 12 weeks reduce body weight body mass index people overweight early research shows taking combination gymnema hydroxycitric acid niacin-bound chromium mouth reduce body weight people overweight obese cough increasing urine excretion diuretic malaria metabolic syndrome snake bites softening stool laxative stimulating digestion more evidence needed rate gymnema uses side effects side effects safety gymnema possibly safe taken mouth appropriately 20 months special precautions warnings pregnancy breast-feeding there not enough reliable information safety taking gymnema you pregnant breast feeding stay safe side avoid diabetes gymnema lower blood sugar levels people diabetes watch signs low blood sugar hypoglycemia.

monitor blood sugar carefully you have diabetes gymnema surgery gymnema affect blood sugar levels interfere blood sugar control during surgical procedures stop using gymnema least weeks scheduled surgery interactions interactions moderate interaction cautious combination insulin interacts gymnema gymnema decrease blood sugar insulin used decrease blood sugar taking gymnema along insulin cause blood sugar low monitor blood sugar closely dose insulin need changed medications diabetes antidiabetes drugs interacts gymnema gymnema supplements seem lower blood sugar people diabetes diabetes medications used lower blood sugar taking gymnema along diabetes medications cause blood sugar go low monitor blood sugar closely dose diabetes medication need changed medications used diabetes include glimepiride amaryl glyburide diabeta glynase prestab micronase insulin pioglitazone actos rosiglitazone avandia chlorpropamide diabinese glipizide glucotrol tolbutamide orinase others dosing dosing appropriate dose gymnema depends several factors user age health several conditions time there not enough scientific information determine appropriate range doses gymnema keep mind natural products not always necessarily safe dosages important sure follow relevant directions product labels consult pharmacist physician healthcare professional using previous next uses view references references ananthan r latha pari ramkumar baskar c g bai v effect.

gymnema montanum blood glucose plasma insulin carbohydrate metabolic enzymes alloxan-induced diabetic rats j med food 2003 43-49 view abstract baskaran ahamath bk shanmugasundaram kr et antidiabetic effect leaf extract from gymnema sylvestre non-insulin-dependent diabetes mellitus patients j ethnopharm 1990 30 295-305 bishayee chatterjee hypolipidaemic antiatherosclerotic effects oral gymnema sylvestre r br leaf extract albino rats fed high fat diet phytother res 1994 118-120 chattopadhyay rr possible mechanism antihyperglycemic effect gymnema sylvestre leaf extract part gen pharm 1998 31 495-496 gholap kar effects inula racemosa root gymnema sylvestre leaf extracts regulation corticosteroid induced diabetes mellitus involvement thyroid hormones pharmazie 2003 58 413-415 view abstract gupta ss variyar mc experimental studies pituitary diabetes iv effect gymnema sylvestre coccinia indica against hyperglycemia response somatotrophin corticotrophin hormones indian j med res 1964 52 200-207 jiang h advances study hypoglycemic constituents gymnema sylvestre retz schult zhong.yao cai 2003 26 305-307 view abstract khare ak tondon rn tewari jp hypoglycaemic activity indigenous drug gymnema sylvestre gurmar normal diabetic persons indian j physiol pharm 1983 27 257-258 kothe uppal r antidiabetic effects gymnema sylvestre.

short study indian j homeopath med 1997 32 1-2 61-62 66 murakami murakami kadoya et new hypoglycemic constituents gymnemic acid from gymnema sylvestre chem pharm bull 1996 44 469-471 okabayashi y tani fujisawa koide hasegawa h nakamura fujii otsuki effect gymnema sylvestre r.br glucose homeostasis rats diabetes res clin pract 1990 143-148 view abstract porchezhian dobriyal r overview advances gymnema sylvestre chemistry pharmacology patents pharmazie 2003 58 5-12 view abstract preuss h g garis r bramble j d bagchi d bagchi rao c v satyanarayana efficacy novel calcium potassium salt -hydroxycitric acid weight control int.j clin.pharmacol.res 2005 25 133-144 view abstract shanmugasundaram erb gopinath kl shanmugasundaram kr et al possible regeneration islets langerhans streptozotocin-diabetic rats given gymnema sylvestre leaf extracts j ethnopharm 1990 30 265-279 shanmugasundaram erb rajeswari g baskaran et al gymnema sylvestre leaf extract control blood glucose insulin-dependent diabetes mellitus j ethnopharm 1990 30 281-294 shanmugasundaram kr panneerselvam c samudram et al enzyme changes glucose utilisation diabetic rabbits effect gymnema sylvestre r.br j ethnopharm 1983 205-234 sinsheimer je rao gs mcilhenny hm constituents from gymnema sylvestre.

leaves v isolation preliminary characterization gymnemic acids j pharm sci 1970 59 622-628 srivastava y bhatt hv prem et al hypoglycemic life-prolonging properties gymnema sylvestre leaf extract diabetic rats israel j med sci 1985 21 540-542 terasawa h miyoshi imoto effects long-term administration gymnema sylvestre watery-extract variations body weight plasma glucose serum triglyceride total cholesterol insulin wistar fatty rats yonago acta med 1994 37 117-127 tominaga kimura sugiyama et al effects seishin-renshi-in gymnema sylvestre insulin resistance streptozotocin-induced diabetic rats diabet res clin pract 1995 29 11-17 wang lf luo h miyoshi et al inhibitory effect gymnemic acid intestinal absorption oleic acid rats j physiol pharmacol 1998 76 1017-1023 xie j wang mehendale wu j aung h h dey qiu yuan c anti-diabetic effects gymnema yunnanense extract pharmacol res 2003 47 323-329 view abstract yoshikawa murakami kadoya li y murakami yamahara j matsuda h medicinal foodstuffs ix inhibitors glucose absorption from leaves gymnema sylvestre r br asclepiadaceae structures gymnemosides chem.pharm bull tokyo 1997 45 1671-1676 view abstract ananthan r baskar c narmathabai v et al antidiabetic effect gymnema montanum leaves effect lipid peroxidation induced oxidative stress experimental diabetes pharmacol res 2003 48 551-6 view abstract arunachalam kd arun lb annamalai sk arunachalam potential anticancer properties bioactive compounds gymnema sylvestre its biofunctionalized silver nanoparticles int j nanomedicine 2014 31-41.

view abstract baskaran kizar ahamath radha shanmugasundaram shanmugasundaram er antidiabetic effect leaf extract from gymnema sylvestre non-insulin-dependent diabetes mellitus patients j ethnopharmacol 1990 30 295-300 view abstract fabio gd romanucci v de marco zarrelli triterpenoids from gymnema sylvestre their pharmacological activities molecules 2014 19 10956-81 view abstract head ka type diabetes prevention disease its complications townsend letter doctors patients 1998 180 72-84 kamble gupta moothedath khatal janrao jadhav et al effects gymnema sylvestre extract pharmacokinetics pharmacodynamics glimepiride streptozotocin induced diabetic rats chem biol interact 2016 245 30-8 view abstract katsukawa h imoto ninomiya y induction salivary gurmarin-binding proteins rats fed gymnema-containing diets chem senses 1999 24 387-92 view abstract luo h kashiwagi shibahara yamada decreased bodyweight without rebound regulated lipoprotein metabolism gymnemate genetic multifactor syndrome animal mol cell biochem 2007 299 93-8 view abstract nakamura y tsumura y tonogai y shibata fecal steroid excretion increased rats oral administration gymnemic acids contained gymnema sylvestre leaves j nutr 1999 129 1214-22 view abstract persaud sj al-majed h raman jones pm gymnema sylvestre stimulates insulin release vitro increased membrane permeability j endocrinol 1999 163 207-12 view abstract preuss hg bagchi d bagchi et al effects natural extract -hydroxycitric acid hca-sx combination hca-sx plus niacin-bound chromium gymnema sylvestre extract weight loss diabetes obes metab 2004 171-180 view abstract rammohan samit chinmoy d et al.

human cytochrome p450 enzyme modulation gymnema sylvestre predictive safety evaluation lc-ms ms pharmacogn mag 2016 jul 12 suppl s389-s394 view abstract satdive rk abhilash fulzele dp antimicrobial activity gymnema sylvestre leaf extract fitoterapia 2003 74 699-701 view abstract shanmugasundaram er rajeswari g baskaran et al gymnema sylvestre leaf extract control blood glucose insulin-dependent diabetes mellitus j ethnopharmacol 1990 30 281-94 view abstract shiyovich sztarkier nesher toxic hepatitis induced gymnema sylvestre natural remedy type diabetes mellitus j med sci 2010 340 514-7 view abstract singh vk dwivedi chaudhary br singh r immunomodulatory effect gymnema sylvestre r.br leaf extract vitro study rat model plos 2015 10 e0139631 view abstract sinsheimer je subba-rao g mcilhenny hm constitents from g sylvestre leaves isolation preliminary characterization gymnemic acids j pharmacol sci 1970 59 622-8 tiwari mishra bn sangwan ns phytochemical pharmacological properties gymnema sylvestre important medicinal plant biomed res int 2014 2014 830285 view abstract vaghela iyer pandita vitro inhibitory effect gymnema sylvestre extracts total gymnemic acids fraction select cytochrome p450 activities rat liver microsomes eur j drug metab pharmacokinet 2017 oct view abstract vaghela sahu kharkar pandita vivo pharmacokinetic interaction ethanolic extract gymnema sylvestre cyp2c9 tolbutamide cyp3a4 amlodipine cyp1a2 phenacetin.

rats chem biol interact 2017 dec 25 278 141-151 view abstract yeh gy eisenberg dm kaptchuk tj phillips rs systematic review herbs dietary supplements glycemic control diabetes diabetes care 2003 26 1277-94 view abstract zuniga ly gonzalez-ortiz martinez-abundis effect gymnema sylvestre administration metabolic syndrome insulin sensitivity insulin secretion j med food 2017 aug 20 750-54 view abstract more resources gymnema reviews 59 interaction checker search another vitamin alpha lipoic acid apple cider vinegar black cohosh calcium chromium coenzyme q ‒ dhea flaxseed folic acid ginko glucosamine melatonin niacin magnesium probiotics red yeast rice st john wort vitamin c vitamin d vitamin show more show less you like choose vitamins supplements vitamins you need you age habits longer life non-drug migraine treatments alternative treatments migraines alternative treatments ibs-d eat stay sharp longevity diet dangers high potassium potassium high find more vitamins used treat conditions diabetes metabolic syndrome weight loss show more show less conditions important information information meant supplement not replace advice from doctor healthcare provider not meant cover possible uses precautions interactions adverse effects information may not fit specific health circumstances never delay disregard seeking professional medical advice from doctor qualified health care provider because something you have read webmd you should always speak doctor health care professional.

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Gimnema

Polluted Air Should be Monitored

Biology: monitoring of levels of polluted in the air is needed.
Want to lose weight? Just stop breathing. It is as easy as that. Pregnant rats in China got fat because they breathed in polluted air.  People face the same problem.  Babies being born fatter may be desired.  However, it could indicate a lifetime of illness for those living in polluted regions.

The rat's cholesterol went through the roof. They also became insulin resistant with diabetes just a short way down the track. Livers and lungs were inflamed. The longer they breathed the bad air, the fatter they got. Baby rats from the pregnant females were much sicker.
Polluted air in Chinese city
Inflammation per se is directly related to obesity which is a precursor to diabetes, or even synonymous with it. Cancer, stroke and heart attacks are related to bad air. Poor health from polluted air is not just a Chinese problem. Western countries do not monitor bad air very intensely. A case in point is Brisbane in Australia where it is measured at three sites well away from the city centre.

Pressure is mounting to set up a federally funded monitoring system so people can keep their stay in polluted areas to a minimum. Factories continue to ignore guidelines at their whim. Australia did have enforced regulations in the 1990s,
but monitoring was stopped.
 Biology by Ty Buchanan 
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BAD AIR 
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Insurance Companies to Force Genetic Testing

Life insurance is a con. We all know that. They take your money. Then when you make a claim they force you into court to make you back down or run you up a huge legal bill. I cashed my life insurance in when they stopped paying the share investment bonus that doubled what you paid in. Now if you close the policy you get back "less" than you paid in premiums.
Insurance companies want compulsory genetic testing
No one is perfect out there, so when they say they will make people have genetic tests before they can take out a policy you should be afraid. The big three insurers say they have not had one complaint from consumers so far. Unfortunately, the ones who had genetic tests have not made any claims yet. There will thousands of complaints when the insurance companies fail to pay out.

Thankfully, you cannot be forced to have a genetic test currently. However, you must hand one over if you have already had one - by law. Just why the government made giving up private information compulsory under force of law is a mystery.

Of those who have had a test or have had one when instructed by insurers (400), a very high 20 percent were refused cover. This is much higher than the half a million who gained cover without a test.
Genetics  by Ty Buchanan
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Australia's Exports of Genetic Material is Growing

Animal genetics in Australia is going strong. Exports of genetic material is growing particularly in Columbia, Chile and Mexico. The world generally is its oyster. 
Australian animal genetic exports semen
Semen is the primary export product. Chile imports bovine semen while sheep and goat semen is purchased by Columbia. Latin America is the main market. Australia has a way to go to reach the U.S. and Canada. However, it is quickly catching up.

The quality of Australian beef is high and breeds suit the climate of South America. Sheep and goats are highly regarded. Surprisingly, even canine semen is exported to SA. Embryos are also sent there.
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New Compunds in a Database to Fight Infection

When things get tough people will try anything. Antibiotics are no longer working, so researchers are asking for newly mixed compounds by chemists to be sent along to them. This a new project set up by the University of Queensland.
Superbugs in a petri dish
The belief is that scientists are working on the same middle of the road compounds. It is in new compounds where hope lies. Every day new compounds are made and just discarded. They are never screened to see what they can do against pathogens.

Community for Open Antimicrobial Drug Discovery (CO-ADD researchers located at UQ are ready to test the compounds against fungi and bacteria, especially superbugs. This will work because rights remain with the chemists who provide the samples.

Funding has been been gained from sources in Australia, New Zealand, the U.S., France and India. The project began in February and will be ongoing. Prevalent diseases like malaria an dengue fever will be included in the target list. The database will be open to the public.
 
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Vaccine for Rheumatoid Arthritis

Rheumatoid arthritis is a widespread complaint. It is usually a malady of the elderly, but the young can succumb to it too. About the only treatment available is replacement of joints with artificial ones and analgesics.
Rheumatoid arthritis treatment vaccine
A team at the University of Queensland has taken a new approach. They have developed a vaccine. Many diseases are caused by the body attacking its own tissue. Arthritis is one of these. If the immune response is suppressed, inflammation decreases. This is how the new vaccine works.

All Westerners have high inflammation levels. This may be a good thing to fight injuries. However, continued long term inflammation does damage to the body. Once switched on and the immediate danger solved it needs to be turned off.

The new method involves taking a sample of the patient's immune cells which are then modified in the lab. This is injected back into the patient. The immune system no longer sees the modified peptide as foreign.

Other problematic diseases due to a lingering immune response would seem to be future candidates for similar vaccines.
Health by Ty Buchanan
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Women Will Not be Needed to Carry Babies

The time when women choose to have babies has changed through history. At the beginning of the 20th century, Doctors told women to wait until they were at least 24 to become pregnant, because it was known that giving births earlier resulted in "damaged" babies due to the lack of medical knowledge at the time.  Waiting too long, however, also resulted in fertility problems. Of course, much of this advice went by the wayside as lack of reliable contraception led to birthing at a younger age anyway.

The Great Depression put a real "stymie" on women choosing to have children in their twenties. Lack of income reduced interest in sex and men told their wives to not fall pregnant. At least this is what we are told.

War in the late 1930s saw all of this self-control fall away as couples fell pregnant with the view that one could be dead tomorrow. Even in 1942 a doctor said people were selfish and wanted creature comforts more than children. How he came to this conclusion is a mystery. With a war on there wasn't much to buy. All labor was directed to the war effort.

After the War, the predilection for early childbirth continued. Male dominated society saw women tied to the home. When war ended people wanted to get back a stable family life as soon as possible.  Too much conflict and death can do this.

The birth control pill was established in the 1960s. This was a whole new ball game. Women could now choose when to have children. By the 1970s the number of women giving birth in their thirties doubled. This rate has continues to rise to the present day.

Culture changed along with this. More women entered the workforce as having two incomes was necessary for the high demand way of life that was developing. Two incomes were not necessary for a couple to live in past eras. People today want everything that our forebears did not have like cars, homes, air conditioning, private schools, quality health care and more importantly, safe workplaces.

Will the future continue along the same path. We do not know. Technology keeps moving forward. It is possible that eventually the human body will not be necessary to carry babies. They are conceived in a dish so perhaps they will be "carried" in some sort of chemical container.
Culture by Ty Buchanan
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