Showing posts with label synthetic. Show all posts
Showing posts with label synthetic. Show all posts

Six-Letter Genetic Code Creates New Life

    | .. .. Uniques life forms are being made in a laboratory a brave new world. genetic for code share twitter facebook reply report genetic science life replies genetic guardian dna synthetic code microbes australia romesberg media genetic on code it six-letter expanded research organisms edition scientists cells years forms genetic go code at six-letter rhysgethin email die living nature biology long adding letters god genetic if code in six-letter work material modified europe asia tech economy environment politics genetic at code to six-letter home create sign wrong times told life-forms change molecule team drugs bases molecules conditions masterclasses genetics prize editor humans molecular carry engineered published proteins | news stories | .. .. |
Beware, science is going down unexplored roads. Bacteria that are semi-synthetic are being created with a six-letter genetic code. New forms of life useful to Man could be on offer.  Hopefully, they will be used in medical treatment. | .. .. not stories news. | .. |
Base six DNA organism
"Normal" life has a base of four letters. Escherichia coli is a bacteria which has a synthetic pair of X and Y blended into it. The six bases stay together despite not conforming to the usual ruling double helix model.  | .. .. | australian| .. .. |   

The E. coli was manipulated to more readily take the pair into its DNA. Also the Y base was made easier for the searching enzymes to find. Bacteria that resisted the pair were selected out to create an ideal "host" E.coli. | .. .. | not. | .. ..

We are a long way from having practical helper organisms. Maybe ten years down the track there will something we can use. Until then it will remain a dream.    | .. .. | not | .. .. |
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New Dye was Adopted Quickly in the 18th Century

Despite this being a "scientific"age, not everything is known about the technology of the past.  New research shows that adoption of new things was quite rapid in the 19th century  For example, a dye was being used industrially only four years after its invention.
Methyl violet dye used to make a 19th century dress
Examination of purple threads from dresses by molecular spectroscopy shows that shows that it was widely used by consumers. Before synthetic dyes were developed only royalty could afford purple dresses as existing dyes were made from molluscs.

After analysis using thin layer chromatography, energy dispersive x-ray and enhanced Raman spectroscopy a dye was identified in three dresses as being methyl violet. It was invented in 1861 and in shops by 1865, Even today getting a new product to market is usually only done with computer related merchandise.
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Synthetic Heart Repair Conduit

Treatment for heart disease is advancing at a rapid pace. Soon, a tiny piece of artery will be removed from a patient and a new heart conduit will be formed. This is for minor problems in the heart, less that 5mm wide.

Conduits are also being made from synthetic materials. Toleration of foreign substances is not a problems because it degrades quickly. They are used to go over the outside of a graft to stop bleeding. The synthetic conduits are made of a fine poly-(glycerol sebacate) net coated with polycaprolactone and the anticoagulant heparin. Mesh holes are too small for blood to pass through. Nothing of the implant remains after three months. A new structure of endogenous cells with M2 macrophages (which reduces inflammation) remains.

Though tests have only been done on rats, use in humans will probably be just as successful. Large grafts using the material will be done to see if this is feasible. This will be a welcome advance in medicine. A graft made of the body's own tissue will last much longer and patients will not need to be treated again for obstruction in the new graft.
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